京都大学大学院医学研究科 血液・腫瘍内科学

研究

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臨床研究グループ

2020年の業績

  • Wada F, Nishikori M, Hishizawa M, Watanabe M, Aiba A, Kitano T, Shimazu Y, Shindo T,Kondo T , and Takaori-Kondo A. Secondary failure of platelet recovery in patients treated with high-dose thiotepa and busulfan followed by autologous stem cell transplantation. Int J Hematol. 112(5): 609-613, 2020.
  • Noguchi M, Chen-Yoshikawa TF, Arai YArai Y, MD, Kondo T, Hiramatsu H, Tanaka S, Yamada Y, Yutaka Y, Nakajima D, Hamaji M, Ohsum A, Takita J, Takaori-Kondo A, Date H. Expanded indications for lung transplantation for pulmonary complications after hematopoietic stem cell transplantation. J Thorac Cardiovasc Surg. 20: 32887-7, 2020.
  • Terakura S, Konuma T, Tanaka M, Ozawa Y, Onizuka M, Nanno S, Onishi Y, Aotsuka N, Kondo T, Kawakita T, Kato J, Kobayashi T, Nishida T, Yamaguchi T, Kuwatsuka Y, and Takahashi S. A randomized control trial of conditioning regimen for cord blood transplantation for adult myeloid malignancies comparing high-dose cytarabine/cyclophosphamide/total body irradiation with versus without G-CSF priming: G-CONCORD study protocol.BMJ Open .10(12): e04067, 2020.
  • 森本 俊、進藤 岳郎、伊賀 雄平、森田 真梨、万木 紀美子、増田 健太、堀 利行、菱澤 方勝、近藤 忠一、山下 浩平、羽賀 博典、髙折 晃史。17年にわたる寒冷凝集素症の経過後に顕在化しibrutinibが著効した小型B細胞腫瘍。臨床血液. 62(12): 1678-1683, 2021.
  • 松浦 朋子, 黒澤 彩子, 山口 拓洋, 森 文子, 森 毅彦, 田中 正嗣, 近藤 忠一, 坂本 周子, 藤井 伸治, 一戸 辰夫, 奈良 美保, 前田 智也, 藤澤 信, 名和 由一郎, 中邑 幸伸, 南口 仁志, 大西 康, 高野 久仁子, 高橋 都, 福田 隆浩。同種移植後患者の就労に関する実態調査 -慢性GVHD等の自覚症状による仕事・生活への影響に関する検討-。日本造血細胞移植学会雑誌。2021, in press.
  • 岡田慎理、北脇年雄、鈴木優太、堀澤欣史、近藤忠一、谷澤公伸、菱澤方勝、高橋良一、山下浩平、高折晃史。同種骨髄移植によって骨髄異形成症候群に伴う二次性肺胞蛋白症が軽快した1例。日本内科学会雑誌. 109: 960-967, 2020.
  • Yamasaki S, Mori J, Kanda J, Imahashi N, Uchida N, Doki N, Tanaka M, Katayama Y, Eto T, Ozawa Y, Takada S, Onizuka M, Hino M, Kanda Y, Fukuda T, Atsuta Y, Yanada M. Effect of allogeneic HCT from unrelated donors in AML patients with intermediate- or poor-risk cytogenetics: a retrospective study from the Japanese Society for HCT. Ann Hematol. 99: 2927-2937, 2020
  • Watanabe M, Kanda J , Kojima H, Ikeda N, Fuji S, Kanda Y, Saji H, Tanaka H. Wide availability of HLA-matched or a few loci-mismatched donors in the graft-vs-host direction among nonsibling first-degree relatives. Hla. 95: 543-554, 2020
  • Watanabe M, Kanda J , Hishizawa M, Nishikori M,Kondo T , Yamashita K, Takaori-Kondo A. Lymphopenia at diagnosis predicts survival of patients with immunodeficiency-associated lymphoproliferative disorders. Ann Hematol. 99(7): 1565-1573, 2020
  • Nakaya A, Tanaka H, Yagi H, Ohta K, Shibayama H, Kohara T,Kanda J , Shindo M, Shimura Y, Kosugi S, Kida T, Kaneko H, Imada K, Karasuno T, Matsuda M, Iida M, Adachi Y, Fuchida SI, Uoshima N, Uchiyama H, Takahashi R, Matsui T, Wada K, Kiyota M, Shimazaki C, Hino M, Kuroda J, Kanakura Y, Takaori-Kondo A, Nomura S, Matsumura I. Retrospective analysis of plasmacytoma in Kansai Myeloma Forum Registry. Int J Hematol. 112: 666-673, 2020
  • Nakaya A, Kohara T, Shibayama H, Onda Y, Kanda J, Kaneko H, Imada K, Kida T, Kosugi S, Ishikawa J, Yamamura R, Shimazu Y, Tanaka H, Fuchida SI, Shimura Y, Kiyota M, Wada K, Ito T, Uoshima N, Yagi H, Yoshihara S, Ohta K, Shimazaki C, Hino M, Takaori-Kondo A, Kuroda J, Matsumura I, Kanakura Y, Nomura S. Retrospective multi-center study of Adolescent and Young Adult (AYA) Multiple Myeloma in Kansai Myeloma Forum registry.Int J Hematol . 112: 435-438, 2020
  • Miyao K, Terakura S, Kimura F, Konuma T, Miyamura K, Yanada M, Kako S, Morhishima S, Uchida N, Toya T, Ozawa Y, Fukuda T, Tanaka M, Sawa M, Takada S, Yoshida S, Kimura T, Ichinohe T, Atsuta Y, Kanda J. Updated Comparison of 7/8 HLA Allele-Matched Unrelated Bone Marrow Transplantation and Single-Unit Umbilical Cord Blood Transplantation as Alternative Donors in Adults with Acute Leukemia.Biol Blood Marrow Transplant . 26: 2105-2114, 2020
  • Kurosawa S, Yamaguchi H, Yamaguchi T, Fukunaga K, Yui S, Kanamori H, Usuki K, Uoshima N, Yanada M, Takeuchi J, Mizuno I, Kanda J, Okamura H, Yano S, Tashiro H, Shindo T, Chiba S, Tomiyama J, Inokuchi K, Fukuda T. The prognostic impact of FLT3-ITD, NPM1 and CEBPa in cytogenetically intermediate-risk AML after first relapse. Int J Hematol. 112: 200-209, 2020
  • Kurosawa S, Shimomura Y, Tachibana T, Ishiyama K, Ota S, Kobayashi T, Uchida N, Fukushima K, Ashida T, Matsuoka KI, Kanda J, Ichinohe T, Atsuta Y, Murata M, Aoki J. Outcome of Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Myelodysplastic/Myeloproliferative Neoplasms-Unclassifiable: A Retrospective Nationwide Study of the Japan Society for Hematopoietic Cell Transplantation.Biol Blood Marrow Transplant . 26: 1607-1611, 2020
  • Kanda J, Ando T, Kimura SI, Fujiwara SI, Imada K, Fujisawa S, Tachibana T, Atsuta Y, Kanda Y. Hematopoietic Stem Cell Transplantation From a Related Donor with Human Leukocyte Antigen 1-Antigen Mismatch in the Graft-Versus-Host Direction Using Low-dose Anti-thymocyte Globulin. Cell Transplant. 29:963689720976567, 2020
  • Ikeda K, Ohto H, Yamada-Fujiwara M, Okuyama Y, Fujiwara SI, Muroi K, Mori T, Kasama K, Kanamori H, Iseki T, Nagamura-Inoue T, Kameda K, Kanda J Nagai K, Fujii N, Ashida T, Hirose A, Takahashi T, Minakawa K, Tanosaki R. Hematopoietic cell infusion-related adverse events in pediatric/small recipients in a prospective/multicenter study. Transfusion. 60: 1015-1023, 2020
  • Hamada R, Kondo T, Murao M, Miyasaka J, Yoshida M, Nankaku M, Kanda J, Takaori-Kondo A, Ikeguchi R, Matsuda S. Effect of the severity of acute graft-versus-host disease on physical function after allogeneic hematopoietic stem cell transplantation. Support Care Cancer. 28(7): 3189-3196, 2020.
  • Morita-Fujita M, Arai Y, Yoshioka S, Ishikawa T, Kanda J, Kondo T, Akasaka T, Ueda Y, Imada K, Moriguchi T, Yago K, Kitano T, Yonezawa A, Nohgawa M, and Takaori-Kondo A on behalf of Kyoto Stem Cell Transplantation Group (KSCTG). Indication and benefit of upfront hematopoietic stem cell transplantation for T-cell lymphoblastic lymphoma in the era of ALL-type induction therapies. Sci Rep. 10(1): 21418, 2020.
  • Iemura T, Arai Y, Kanda J, Kitawaki T, Hishizawa M, Kondo T, Yamashita K, Takaori-Kondo A. Impact of HLA class I allele-level mismatch on viral infection within 100 days after cord blood transplantation. Sci Rep. 10(1): 21150, 2020.
  • Akahoshi Y, Nishiwaki S, Arai Y, Harada K, Najima Y, Kanda Y, Shono K, Ota S, Fukuda T, Uchida N, Shiratori S, Tanaka M, Tanaka J, Atsuta Y, Kako S. Reduced-intensity Conditioning Is a Reasonable Alternative for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Among Elderly Patients Who Have Achieved Negative Minimal Residual Disease: A Report From the Adult Acute Lymphoblastic Leukemia Working Group of the JSHCT. Bone Marrow Transplant.55(7): 1317-1325, 2020.
  • Imahashi N, Terakura S, Kondo E, Kako S, Uchida N, Kobayashi H, Inamoto Y, Sakai H, Tanaka M, Ishikawa J, Kozai Y, Matsuoka KI, Kimura T, Fukuda T, Atsuta Y, Kanda J; Donor/Source Working Group of the Japan Society for Hematopoietic Cell Transplantation. Comparison of Reduced-Intensity/Toxicity Conditioning Regimens for Umbilical Cord Blood Transplantation for Lymphoid Malignancies. Bone Marrow Transplant. 55(11):2098-2108,2020.
  • Yanada M, Takami A, Yamasaki S, Arai Y, Konuma T, Uchida N, Najima Y, Fukuda T, Tanaka M, Ozawa Y, Ikegame K, Takanashi M, Ichinohe T, Okamoto S, Atsuta Y, Yano S. Allogeneic Hematopoietic Cell Transplantation for Adults With Acute Myeloid Leukemia Conducted in Japan During the Past Quarter Century. Ann Hematol.99(6): 1351-1360, 2020
  • Yamamoto S, Tomizawa D,Kudo K, Hasegawa D, Taga T, Yanada M, Kondo T , Nakazawa Y, Eto T, Inoue M, Kato K, Atsuta Y and Ishida H. Hematopoietic stem cell transplantation for pediatric acute promyelocytic leukemia in Japan. Pediatric Blood &Cancer .67(5): e28181, 2020.
  • Yokoyama H, Takenaka K, Nishida T, Seo S, Shinohara A, Uchida N, Tanaka M, Takahashi S, Onizuka M, Kozai Y, Yasuhiro S, Ozawa Y, Katsuoka Y, Doki N, Sawa M, Kimura T, Kanda J, Fukuda T, Atsuta Y, Nakasone H; Japan Society for Hematopoietic Cell Transplantation Transplantation-Related Complication Working Group. Favorable Effect of Cytomegalovirus Reactivation on Outcomes in Cord Blood Transplant and Its Differences Among Disease Risk or Type. Biol Blood Marrow Transplant . 26(7): 1363-1370, 2020.
  • Kaito S, Nakajima Y, Hara K, Toya T, Nishida T, Uchida N, Mukae J, Fukuda T, Ozawa Y, Tanaka M, Ikegame K, Katayama Y, Kuriyama T, Kanda J, Atsuta Y, Ogata M, Taguchi A, Ohashi K. Heterogeneous Impact of Cytomegalovirus Reactivation on Nonrelapse Mortality in Hematopoietic Stem Cell Transplantation. Blood Adv .4(6): 1051-1061, 2020 .
  • Kawamura K, Kanda J, Ohashi K, Fukuda T, Iwato K, Eto T, Fujiwara SI, Mori T, Fukushima K, Ozawa Y, Uchida N, Ashida T, Ichinohe T, Atsuta Y, Kanda Y. Influence of HLA 1-3-locus Mismatch and Antithymocyte Globulin Administration in Unrelated Bone Marrow Transplantation. Ann Hematol . 99(5): 1099-1110,2020.
  • Watanabe M, Kanda J, Arai Y, Hishizawa M, Nishikori M, Ishikawa T, Imada K, Ueda Y, Akasaka T, Yonezawa A, Nohgawa M, Kitano T, Itoh M, Takeoka T, Moriguchi T, Yago K, Arima N, Anzai N, Watanabe M, Kondo T, Takaori-Kondo A, on behalf of the Kyoto Stem Cell Transplantation Group (KSCTG). Impact of donor source on allogeneic hematopoietic stem cell transplantation for mature T- and NK-cell neoplasms in the Kyoto Stem Cell Transplantation Group. Biol Blood Marrow Transplant. 26(12): 2346-2358, 2020.
  • Nagahata Y, Kondo T, Ono Y, Hiramoto N, Kitano T, Hishizawa M, Yamashita K, Hashimoto H, Ishikawa T, Takaori-Kondo A. High-Dose Cytarabine Chemotherapy (≥4 g/m2/day) before Allogeneic Hematopoietic Stem Cell Transplantation for Non-Core-Binding-Factor AML in the First Complete Remission. Leuk Lymohoma. 61(13): 3128-3136, 2020.
  • Kanda J, Umeda K, Kato K, Murata M, Sugita J, Adachi S, Koh K, Noguchi M, Goto H, Yoshida N, Sato M, Koga Y, Hori T, Cho Y, Ogawa A, Inoue M, Hashii Y, Atsuta Y, Teshima T; JSHCT GVHD Working Group. Effect of Graft-Versus-Host Disease on Outcomes After Pediatric Single Cord Blood Transplantation. Bone Marrow Transplant . 55(7): 1430-1437,2020.
  • Harada K, Fuji S, Seo S, Kanda J, Ueki T, Kimura F, Kato K, Uchida N, Ikegame K, Onizuka M, Matsuoka KI, Doki N, Kawakita T, Onishi Y, Yano S, Fukuda T, Takanashi M, Kanda Y, Atsuta Y, Ogata M; transplant complications working group of the Japan Society for Hematopoietic Cell Transplantation. Comparison of the Outcomes After Haploidentical and Cord Blood Salvage Transplantations for Graft Failure Following Allogeneic Hematopoietic Stem Cell Transplantation. Bone Marrow Transplant . 55(9): 1784-1795,2020.
  • Fujimoto A,Hiramoto N,Yamasaki S,Inamoto Y,Ogata M, Sugio Y, Fukuda T,Uchida N,kegame K, Matsuoka K, Shiratori S, Kondo T,Miyamoto T,Tetsuya T,Ichinohe T,Kanda Y,Atsuta Y,and Suzuki R,on behalf of the Complication Working Group of the Japan Society for Hematopoietic Cell Transplantation. Low incidence of post-transplant lymphoproliferative disorder after allogeneic stem cell transplantation in patients with lymphoma treated with rituximab. Hematol Oncol .38(2): 146-152,2020.
  • Wada F, Kondo T, Nakamura M, Chonabayashi K, Nishikori M, Hishizawa M, Yamashita K, and Takaori-Kondo A. Successful treatment of Hodgkin Lymphoma-like EBV-associated post-transplant lymphoproliferative disorder following allogeneic hematopoietic stem cell transplantation with nivolumab. Ann Hematol . 99(4): 887-889,2020.
  • Wada F, Kondo T, Nakamura M, Uno S, Fujimoto M, Miyamoto T, HOnda Y, Shibata H, Izawa K, Yasumi T, Nishikori M, and Takaori-Kondo A. EBV-associated lymphoproliferative disorder in a patient with X-linked severe combined immunodeficiency with multiple reversions of an IL2RG mutation in T cells.eJHaem . 1(2): 581-584, 2020.
  • Cirasino L, Robino AM, Podda G, Andrès E, Despotovic JM, Elalfy M, Holbro A, Kondo T, Lambert MP, Lee JW, Loggetto SR, McCrae KR, and Cattaneo M. Report of a ‘consensus’ on the lines of therapy for primary immune thrombocytopenia in adults. Platelets .31(4): 461-473,2020.
  • Yamashita T, Takami A, Uchida N, Fukuda T, Eto T, Shiratori S, Ota S, Akasaka T, Miyakoshi S, Kondo T, Hidaka M, Kanda J, Atsuta Y, and Yano S.Reduced-intensity stem cell transplantation for acute myeloid leukemia with fludarabine-based conditioning with intravenous busulfan versus melphalan. Bone Marrow Transplant .55(10): 1955-1965 2020.
  • Kida M, Usuki, K, Uchida N, Fukuda T, Katayama Y, Kondo T, Eto T, Matsuoka KI, Matsuhashi Y, Ota S, Sawa M, Miyamoto T ,Ichinohe T, Kimura T , Atsuta Y, Takami A, Miyazaki Y,Yano S , Ishiyama K ,Yanada M, Aoki J. Outcome and Risk Factors for Therapy-Related Myeloid Neoplasms Treated with Allogeneic Stem Cell Transplantation in Japan. Biol Blood Marrow Transplant .26(8): 1543-1551, 2020.
  • Horisawa Y, Kondo T, Hishizawa M, Yamashita K, Takaori-Kondo A. A case of allogeneic hematopoietic stem cell transplantation for primary plasma cell leukemia after treatment with daratumumab. Ann Hematol . 99(11): 2699-2701,2020.
  • Muranushi H, Kanda J, Arai Y, Shindo T, Hishizawa M, Yamamoto T, Kondo T, Yamashita K, Matsubara K, Takaori-Kondo A. Drug monitoring for mycophenolic acid in graft-versus-host disease prophylaxis in cord blood transplantation. Br J Clin Pharmacol . Br J Clin Pharmacol . 86(12): 2464-2472, 2020.
  • Matsui H, Arai Y, Imoto H, Mitsuyoshi T, Tamura N, Kondo K, Kanda J, Ishikawa T, Imada K, Ueda Y, Akasaka T, Anzai N, Yago K, Nogawa M, Yonezawa A, Arima N, Ito M, Kitano T, Tsuji M, Moriguchi T, Takaori-Kondo A. Risk factors and appropriate therapeutic interventions for thrombotic microangiopathy after allo-HSCT. Blood Adv . 4(13): 3169-3179, 2020.
  • Konuma T, Kondo T, Mizuno S, Doki N, Aoki J, Fukuda T, Tanaka M, Sawa M, Katayama Y, Uchida N, Ozawa Y, Morishige S, Matsuoka KI, Ichinohe T, Onizuka M, Kanda J, Atsuta Y, Yanada M; Adult Acute Myeloid Leukemia Working Group of the Japan Society for Hematopoietic Cell Transplantation. Conditioning Intensity for Allogeneic Hematopoietic Cell Transplantation in Acute Myeloid Leukemia Patients with Poor-Prognosis Cytogenetics in First Complete Remission. Biol Blood Marrow Transplant . 26(3): 463-471, 2020.
  • Shinohara S, Oshima K, Fuji S, Umeda K, Kako S, Kurokawa M, Tsukada N, Kasai M, Kondo T, Hashii Y, Nakamae H, Ikegame K, Kosaka Y, Shimada A, Nawa Y, Makoto Y, Teshima T, Atsuta Y, Fukuda T, Tanaka J and Ogata M. Hematopoietic stem cell transplantation in solid organ recipients with emphasis on transplant complications: a nationwide retrospective survey on behalf of the JSHCT, transplant complications working group. Biol Blood Marrow Transplant . 26(1): 66-75, 2020.
  • Arai Y, Kondo T, Fuse K, Shibasaki Y, Masuko M,Sugita J , Teshima T, Uchida N, Fukuda T, Kakihana K, Ozawa Y, Eto T, Tanaka M, Ikegame K, Mori T, Iwato K, Ichinohe T, Kanda Y, Atsuta Y. Using a machine learning algorithm to predict acute graft-versus-host disease following allogenic transplantation. Blood AdvBlood Adv . 3(22): 3626-3634, 2019.
  • Konuma T, Kanda J, Inamoto Y, Hayashi H, Kobayashi S, Uchida N, Sugio Y, Tanaka M, Kobayashi H, Kouzai Y, Takahashi S, Eto T, Mukae J, Matsuhashi Y, Fukuda T, Takanashi M, Kanda Y, Atsuta Y, Kimura F. Improvement of Early Mortality in Single-Unit Cord Blood Transplantation for Japanese Adults From 1998 to 2017. Am J Hematol. 95(4): 343-353, 2020.
  • Yokoyama H, Morishima Y, Fuji S, Uchida N, Takahashi S, Onizuka M, Tanaka M, Yuju O, Eto T, Ozawa Y, Takada S, Takanashi M, Kato K, Kanda Y, Ichinohe T, Atsuta Y, Kanda J; HLA Working Group of the Japan Society for Hematopoietic Cell Transplantation. Impact of HLA Allele Mismatch at HLA-A, -B, -C, and -DRB1 in Single Cord Blood Transplantation. Biol Blood Marrow Transplant . 26(3): 519-528, 2020.
  • Kanda J, Hayashi H, Ruggeri A, Kimura F, Volt F, Takahashi S, Labopin M, Kako S, Tozatto-Maio K, Yano S, Sanz G, Uchida N, Van Lint MT, Kato S, Mohty M, Forcade E, Kanamori H, Sierra J, Ohno Y, Saccardi R, Fukuda T, Ichinohe T, Takanashi M, Rocha V, Okamoto S, Nagler A, Atsuta Y, Gluckman E. Prognostic factors for adult single cord blood transplantation among European and Japanese populations: the Eurocord/ALWP-EBMT and JSHCT/JDCHCT collaborative study. Leukemia . 34(1): 128-137, 2020.
  • Yanada M, Konuma T, Yamasaki S, Kuwatsuka Y, Masuko M, Tanaka M, Ozawa Y, Toya T, Fukuda T, Ota S, Sawa M, Uchida N, Nakamae H, Eto T, Kanda J, Takanashi M, Kanda Y, Atsuta Y, Yano S. Time-Varying Effects of Graft Type on Outcomes for Patients with Acute Myeloid Leukemia Undergoing Allogeneic Hematopoietic Cell Transplantation. Biol Blood Marrow Transplant .26(2):307-315, 2020.
  • Kanda J, Kawase T, Tanaka H, Kojima H, Morishima Y, Uchida N, Nagafuji K, Matsuhashi Y, Ohta T, Onizuka M, Sakura T, Takahashi S, Miyakoshi S, Kobayashi H, Eto T, Tanaka J, Ichinohe T, Atsuta Y, Morishima S; HLA Working Group of the Japan Society for Hematopoietic Cell Transplantation. Effects of Haplotype Matching on Outcomes after Adult Single-Cord Blood Transplantation. Biol Blood Marrow Transplant . 26(3): 509-518, 2020.
  • Morishima Y, Morishima S, Murata M, Arima N, Uchida N, Sugio Y, Takahashi S, Matsuhashi Y, Onizuka M, Eto T, Nagafuji K, Onishi Y, Inoue M, Atsuta Y, Fukuda T, Ichinohe T, Kato S, Kanda J. Impact of Homozygous Conserved Extended HLA Haplotype on Single Cord Blood Transplantation: Lessons for Induced Pluripotent Stem Cell Banking and Transplantation in Allogeneic Settings. Biol Blood Marrow Transplant . 26(1): 132-138, 2020.
  • Tamura N, Maeda H, Nishikori M, Fujita H, Hishizawa M, Haga H, Takaori-Kondo A. Histologic transformation of t(11;18)-positive MALT lymphoma presented with aberrant T-cell marker expression. Int J Hematol . 111(5): 724-732, 2020.